Research

Our research emphasizes four dimensions: 1) Innovate; 2) Communicate; 3) Collaborate; 4) Translate.

Our core values are: 1) Integrity; 2) Circle of safety and trust; 3) Learning / openness to new ideas; 4) Effective work habits; 5) Creativity; 6) Teamwork; 7) Scientific excellence.

We pursue interdisciplinary research towards enhanced quantitative image generation and analysis in tomographic medical imaging applications (PET, SPECT, optical, acoustic). Coupled with our provincial functional imaging and therapy program, we emphasize partnerships with other collaborators, clinical sites and industry, aiming for translation of our methods to state-of-the-art patient care and to impact quality of life. Our efforts include:

  • Quantitative PET imaging methods for enhanced diagnosis, prognosis and treatment response assessment of cancer patients (e.g. prostate cancer, lymphoma, lung cancer, …)
  • Radiomics and machine learning methods as applied to PET and SPECT imaging (cancer, cardiovascular disease and Parkinson’s disease)
  • Quantitative SPECT-based dosimetry in radiopharmaceutical therapy (a.k.a. radionuclide or radioligand therapy)
  • Partial volume correction as applied to PET imaging of cancer as well as Alzheimer’s disease
  • Dynamic whole-body PET/CT imaging
  • Statistical tomographic image reconstruction algorithms (including tomosynthesis; e.g. as applied to ultrasound imaging)
  • Optical and photoacoustic imaging through the intact brain for in vivo assessment of brain network activity
  • Cardiac and/or respiratory motion compensation methods (4D/5D imaging)